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Glyceryl Monooleate Excipient | Uses, Suppliers, and Specifications

Glyceryl Monooleate is lipid excipient that consists of several monoglycerides, but principally glyceryl monooleate, but also variable quantities of diglycerides and triglycerides. It is obtained by partial esterification of glycerol with vegetable oils high in oleic acid. It usually includes an antioxidant. Glyceryl monooleate is supplied as an amber-coloured oily liquid that exhibits a characteristic odour.

Synonyms and Trade Names: Glyceryl Monooleate; 9-Octadecenoic acid (Z)-, monoester with 1,2,3-propanetriol; Monoolein; 1-Oleoylglycerol; Glyceryl Oleate; E471; IMWITOR® 948; ALDO HMO; KESSCO GMO; ARLACEL 129; STEPAN GMO; Peceol™

Pharmacopoeial Compliance: USP-NF; Ph.Eur

Uses and Applications: Wetting Agent; Defoamer; Emollient and Emulsifying Agent

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Description

Glyceryl Monooleate is a lipid substance derived by esterification of glycerol with fatty acids, mainly. For this reason, many pharmacopoeia describe Glyceryl monooleate as a mixture of monoglycerides, with the monooleate being the main fatty acid, although present are variable quantities of diglycerides and triglycerides. The commercial material may also include an antioxidant, such as Alpha-tocopherol, Ascorbyl palmitate, Citric acid or Ascorbic acid. GMO is supplied as an amber-coloured liquid or soft solid, with a characteristic lipid odour.

 

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