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Utilising Dynamic Dissolution Testing to Predict Gastrointestinal Behaviour of Modified Release Products

In-vitro dissolution tests that correlate with in vivo behaviour provide a better understanding of bioavailability while also permitting setting of a product’s acceptance criteria and formulation parameters. When developing oral modified release products, formulators often face challenges of selecting optimal test media and protocols with which to conduct such dissolution tests. Catch up in this webinar where we review the concept of dynamic dissolution testing and application to new formulation screening, assessment of inter/intra-subject variability of GI pH and effect on drug release, design of robust modified release formulations using physiologically relevant bicarbonate buffers and batch release testing and quality control.

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